Agents affecting thrombosis and hemostasis

Details Agents affecting thrombosis and hemostasis Agents affecting thrombosis and hemostasis

1998-01-30

1999-10-19

Degen, Nancy

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

424 9464, 424422, 424423, 435212, 530381, 530384, 530830, A61K 3836, A61K 3516, A61F 1300, C07K 14435

Patent

active

059688971

ABSTRACT:
Analogs of blood factors which are transiently inactive are useful in treatment of diseases characterized by thrombosis. In addition, modified forms of activated blood factors that generate the active blood factor in serum but have extended half-lives are useful in treating hemophilic conditions. These modified forms of the blood factor may be acylated forms which are slowly deacylated in vivo.

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patent: 5583107 (1996-12-01), Wolf et al.
patent: 5597799 (1997-01-01), Wolf
patent: 5837679 (1998-11-01), Wolf et al.

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