Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1994-03-11
1995-03-28
Henley, III, Raymond J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 3147
Patent
active
054017548
ABSTRACT:
A pharmaceutical preparation comprising at least one compound selected from the group consisting of carbostyril derivatives having the general formula: ##STR1## wherein R.sup.1 is hydrogen or a lower alkyl group optionally having hydroxy group as a substituent; R.sup.2 is a phenyl(lower alkyl) group optionally having 1 to 3 substituents selected from the group consisting of a lower alkoxy group and a halogen atom on the phenyl ring, pyridyl(lower alkyl) group, or a group of the formula --A--NR.sup.3 R.sup.4 (wherein A is a lower alkylene group, R.sup.3 and R.sup.4 are the same or different and represent a lower alkyl group or phenyl group), and a salt thereof, which is useful as an agent for treating thrombosis, more particularly, as an agent for inhibiting platelet aggregation and as an agent for platelet aggregate dissociation.
REFERENCES:
patent: 3969507 (1976-07-01), Kohri
patent: 4277479 (1981-07-01), Nishi et al.
patent: 4298739 (1981-11-01), Nishi et al.
patent: 4389392 (1983-06-01), Adachi
patent: 5053514 (1991-10-01), Fujioka et al.
Toyoki Mori et al, The Japanese Journal of Pharmacology, The 64th Annual Meeting, Mar. 24-27, 1991, p. 45P.
Fujioka et al, The Pharmaceutical Society of Korea, International Congress of New Drugs Development "Programs and Abstracts", Aug. 18-24, 1991, pp. 44 and 203.
Hiroyuki Fujiki et al, The Japanese Journal of Pharmacology, The 64th Annual Meeting, Mar. 24-27, 1991, p. 158P.
Hosokawa et al, Cardiovascular Actions of OPC-18790: A Novel Positive Inotropic Agent with Little Chronotropic Action, Heart Vessels, 7:66-75, (1992).
Fujioka Takafumi
Teramoto Shuji
Tominaga Michiaki
Yabuuchi Yoichi
Henley III Raymond J.
Jarvis William R. A.
Otsuka Pharmaceutical Company Limited
LandOfFree
Agent for treating thrombosis and phosphodiesterase inhibitor does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Agent for treating thrombosis and phosphodiesterase inhibitor, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Agent for treating thrombosis and phosphodiesterase inhibitor will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2250828