Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2003-11-25
2009-02-24
Solola, Taofiq A (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
C548S952000
Reexamination Certificate
active
07494987
ABSTRACT:
An agent for preventing/treating respiratory diseases contains, as an active ingredient, a compound represented by following Formula (I):wherein A is a group represented by L-W [wherein L is a bond or CH2; and W is O, SOn (wherein n is 0 to 2), or —NR7— (wherein R7is hydrogen or lower alkyl)]; each of G1and G2is (CH2)r (wherein r is 0 to 2), provided that when n is 1, G1and G2may be bridged by lower alkylene; Y is a lower alkylene or (substituted) benzylidene; Z is a bond or O, provided that when Z is a bond, Y may form a 5- or 6-membered ring with carbon on the benzene ring; R1is, for example, NO2, a lower alkoxycarbonyl, (substituted) carbamoyl, (protected) hydroxyl group, (protected) carboxyl, or (protected) N-hydroxycarbamoyl; each of R2and R3is hydrogen, halogen, (halogenated) lower alkyl, (halogenated) lower alkoxy or NO2; each of R4and R5is, for example, hydrogen, halogen, (halogenated) lower alkyl, (halogenated) lower alkoxy, CN, or lower alkylsulfonyl; and R6is hydrogen or lower alkyl, a salt thereof or a solvate of them. It has excellent antitussive activity when used as an agent for preventing/treating respiratory diseases such as lung cancer, common cold syndrome, pulmonary tuberculosis, pneumonia, acute bronchitis or chronic bronchitis.
REFERENCES:
patent: 4508724 (1985-04-01), Taylor, Jr. et al.
patent: 6642257 (2003-11-01), Yamamoto et al.
patent: 6710060 (2004-03-01), Yamamoto et al.
patent: 2004/0176410 (2004-09-01), Yamamoto et al.
patent: 0 152 236 (1985-08-01), None
patent: 0 823 896 (1998-02-01), None
patent: 0 934 271 (1999-08-01), None
patent: WO 93/02052 (1993-02-01), None
patent: WO 96/34857 (1996-11-01), None
patent: WO 98/18761 (1998-05-01), None
patent: WO 00/06544 (2000-02-01), None
patent: WO 00/06545 (2000-02-01), None
patent: WO 00/61557 (2000-10-01), None
patent: WO 00/61558 (2000-10-01), None
patent: WO 02/22572 (2002-03-01), None
patent: WO 02/096875 (2002-12-01), None
Bruno S. Huegi et al.; “Synthesis and Pharmacological Studies of 4,4-Disubstituted Piperidines: A New Class of Compoundswith Potent Analgesic Properties”; J. Med. Chem.; 1983; vol. 26; pp. 42-50.
Akada Yasushige
Matsuura Kazuyuki
Mochida Pharmaceutical Co. Ltd.
Oliff & Berridg,e PLC
Solola Taofiq A
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