Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-01-17
1990-02-27
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
A61K 31445
Patent
active
049046730
ABSTRACT:
(.+-.)-1-[4-[Ethyl[2-(4-methoxyphenyl)-1-methylethyl]-amino]-1-oxobutyl]-N, N-dimethyl-4-piperidine carboxamide and (+)-1-[4-[ethyl[2-(4-methoxyphenyl)-1-methylethyl]-amino]-1-oxobutyl]N,N-d imethyl-4-piperidinecarboxamide, as well as the physiologically acceptable acid addition salts of these compounds are suitable for the treatment of bradycardia and bradyarrhythmia.
REFERENCES:
patent: 4547514 (1985-10-01), Mathur
patent: 4560692 (1985-12-01), Field
De Bree, CA. 110:224807w (1988).
Van Der Stel, CA. 110:204964s (1988).
Buffington, CA. 110:147636k (1989).
Bigler, CA. 106:107814c (1986).
Thomas, CA. 106:12842w (1986).
de Jonge Adriaan
Eberlein Wolfgang
Engel Wolfhard
Mayer Norbert
Mihm Gerhard
Dr. Karl Thomae GmbH
Frankhouser D. E.
Rose Shep K.
Stempel Alan R.
Timbers Mary-Ellen M.
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