Agent for therapeutic treatment of optic nerve diseases and...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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Reexamination Certificate

active

07638516

ABSTRACT:
The medicament for therapeutic and/or prophylactic treatment of the present invention has a suppressing action on the retinal degeneration induced by transient retinal ischemia, which is verified by the results for suppressing effect on retinal degeneration in transient retinal ischemia eye. Therefore, the medicament of the present invention has a therapeutic and/or prophylactic effectiveness on diseases in optic nerve and the like.

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Babovic et al., S. “Role of reactive oxygen species in optic nerve compression injury: A preliminary study.” Annals of Plastic Surgery. United States. ISSN 0148-7043. vol. 40, nr. 2, pp. 156-159 (1998).
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Eschweiler et al., G. W. “Free-radical scavengers support retinal ganglion cell survival after traumatic optic nerve lesions.” 26th Annual Meeting of the Society for Neuroscience; Washington, D.C., USA; Nov. 16-21, 1996. Society for Neuroscience Abstracts, vol. 22, nr. 1-3, p. 317, CONF. (1996).
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