Agent for the TSH suppression and treatment of struma

Details Agent for the TSH suppression and treatment of struma Agent for the TSH suppression and treatment of struma

1991-08-23

1993-04-06

Friedman, S. J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

A61K 31195

Patent

active

052004287

ABSTRACT:
The agent for TSH suppression and for treatment of struma contains a therapeutically effective dose of 3,5-diiodo-L-thyronine and conventional galenic auxiliary materials.

REFERENCES:
Chem. Abst. 89-140 822 G.
Merck Index, p. 423 9th Ed (1976).
G. Hintze et al., "Controlled Study on the Therapeutic Effect of Iodine and Thyroxine in Patients with Simple Goitre," ACTA ENDOCRINOL., Band 102, Suppl. 253, p. 130 (1983).
N. R. Stasilli et al., "Antigoitrogenic and Calorigenic Activities of Thyroxine Analogues in Rats," Endocrinology, Band 64, No. 1, pp. 62-82 (1959).
E. C. Jorgensen et al., "Thyroid Hormone Analogs: Correlations Between Structure, Nuclear Binding and Hormonal Activity," Int. Congr. Ser.-Excerpta Med., Band 403; Endocrinology, Band 2, pp. 117-120 (1977).
C. Horst e al., "Rapid Stimulation of Hepatic Oxygen Consumption by 3,5-di-iodo-L-thyronine," Biochem. J., vol. 261, No. 3, pp. 945-950 (1989).

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