Agent for the treatment of allergic reactions

Details Agent for the treatment of allergic reactions Agent for the treatment of allergic reactions

1979-10-23

1982-08-17

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

260112R, 260112B, A61K 3700, C07G 700

Patent

active

043449387

ABSTRACT:
What are disclosed are a method for the prophylaxis and therapy of allergic reactions and an agent therefor, said agent containing immunoglobulins of class IgG or fragments thereof which have been immunologically modified in their Fc part.

REFERENCES:
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patent: 4164495 (1979-08-01), Hansen
patent: 4190646 (1980-02-01), Goldstein
patent: 4190647 (1980-02-01), Goldstein
patent: 4256631 (1981-03-01), Yokoo et al.
Porter, "The Hydrolysis of Rabbit Gamma-Globulin, etc.", Biochem J. 73, 119-126 (1959).
Haupt et al., "Krystallisation etc", Klin. Wschr. 47, 270-272 (1969).
Nisonoff, "Separation of Univalent Fragments", Arch. Biochem. Biophys. 89 (2), 230(1960), [Abstract only].
Ebeling et al., "Proteinase K etc.", Eur. J. Biochem. 47, 91-97 (1974).
Davies et al., "Preparation of Antibody Fragments etc.", J. Immunol. Methods 21, 305-315 (1978).
Lin et al., "The Action of Proteolytic Enzymes etc.", J. Biol. Chem. 244, 789-793 (1969).
Sachar et al., "Photometric Method etc.", Proc. Soc. Exp. Bio. Med. 90, 323-326 (1955).
Schultze et al., "Molecular Biology of Human Proteins", Elsevier Amsterdam 1966, pp. 41-46.
Miekka et al., "Anticomplementary Activity etc.", Vox Sang. 29, 101-123 (1975).
Franklin et al., "An Unusual Protein etc.", J. Exp. Med. 105, 425-438 (1957).

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