Agent for preventing, improving or treating hypertension

Details Agent for preventing, improving or treating hypertension Agent for preventing, improving or treating hypertension

2008-04-01

2008-04-01

Hoffman, Susan Coe (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Containing or obtained from zingiberaceae

C424S760000

Reexamination Certificate

active

07351436

ABSTRACT:
The invention relates to an agent for preventing, improving or treating hypertension, which exhibits a hypotensive effect, inhibits the rise of blood pressure and improves hypertension, and food for preventing or improving hypertension, which does not become a burden in daily intake, has a higher antihypertensive effect and is useful as a diet during treatment for patients of hypertension. The agent for preventing, improving or treating hypertension contains the following components (A) and (B):(A) a compound selected from the group consisting of caffeic acid, chlorogenic acid and ferulic acid, and esters and pharmaceutically acceptable salts thereof; and(B) a component selected from the group consisting of central nervous system stimulating components, food fibers, extracts of perennial evergreen leaves of the genusCamellia, Theaceae, orEucommia ulmoidesOliver,Eucommiae, organic acids having a molecular weight of 60 to 300 (excluding citric acid) and pharmaceutically acceptable salts thereof, and sugar alcohols.

REFERENCES:
patent: 3068148 (1962-12-01), Freedman et al.
patent: 4434177 (1984-02-01), Vickers
patent: 4981852 (1991-01-01), Ahn
patent: 5883086 (1999-03-01), Craft
patent: 5932623 (1999-08-01), Tanabe et al.
patent: 5958417 (1999-09-01), Hsu
patent: 5994413 (1999-11-01), Tanabe et al.
patent: 6310100 (2001-10-01), Suzuki et al.
patent: 6440464 (2002-08-01), Hsia et al.
patent: 6458392 (2002-10-01), Okawa et al.
patent: 2002/0022062 (2002-02-01), Okawa et al.
patent: 2004/0151790 (2004-08-01), Suzuki et al.
patent: 0 470 895 (1992-02-01), None
patent: 1 090 635 (2001-04-01), None
patent: 2 302 745 (1976-10-01), None
patent: 04243822 (1992-08-01), None
patent: 8-259453 (1996-10-01), None
patent: WO 98/01143 (1998-01-01), None
English abstract of JP 63267255 (1988).
Suekawa et al. (Nippon yakurigaku zasshi. Folia pharmacologia Japonica (1986), vol. 88, No. 5, pp. 339-347).
Neogi et al. (Jour. Res. Ind. Med. (1971), vol. 6, No. 1, pp. 24-29).
V. L. M. Mendonca, et al., Mem. Inst. Oswaldo Cruz, vol. 86, No. Suppl. II, pp. 93-97, XP-008017866, “Pharmacological and Toxicological Evaluation ofAlpinia speciosa”, 1991.
J.-T. Cheng, et al., The Chinese Pharmaceutical Journal, vol. 46, No. 6, pp. 575-582, XP-008007443, “Antihypertensive Activity of Phenolics from the Flower ofLonicera japonica”, 1994.
Database CA ′Online !, Chemical Abstracts, Database Accession No. 124 : 174233, 1 page, XP-002256692, JP 7-327633, Dec. 19, 1995.
Database CA ′Online !, Chemical Abstracts, M. Maruno, Database Accession No. 128 : 336, 1 page, XP-002256693, “Active Principles of Pinelliae Tuber and New Preparation of Crude Drug”, 1997.
Derwent Abstracts, AN 1986-267860, XP-002256694, JP 61-194022, Aug. 28, 1986.
Derwent Abstracts, AN 1992-337587, XP-002219275, JP 04-243822, Aug. 31, 1992.
Derwent Abstracts, AN 1998-460078, XP-002256695, JP 10-191944, Jul. 28, 1998.
Derwent Abstracts, AN 1998-433767, XP-002256697, JP 10-182469, Jul. 7, 1998.
Derwent Abstracts, AN 1995-340204, XP-002256698, JP 07-233081, Sep. 5, 1995.
Derwent Abstracts, AN 1994-111954, XP-002256699, JP 06-056674, Mar. 1, 1994.
Derwent Abstracts, AN 1982-40132E, XP-002256700, JP 57-058609, Apr. 8, 1982.
Derwent Abstracts, AN 1996-091609, XP-002256701, JP 08-000219, Jan. 9, 1996.
Derwent Abstracts, AN 2002-628431, XP-002256702, CN 1-185955, Jul. 1, 1998.
Derwent Abstracts, AN 1997-431394, XP-002256703, JP 09-194377, Jul. 29, 1997.
Derwent Abstracts, AN 1997-431377, XP-002256704, JP 09-194357, Jul. 29, 1997.
Derwent Abstracts, AN 1989-280855, XP-002256705, JP 01-203328, Aug. 16, 1989.
Derwent Abstracts, AN 1980-07618C, XP-002256706, DD 138406, Oct. 31, 1979.
Derwent Abstracts, AN 1999-604900, XP-002256709, JP 11-263733, Sep. 28, 1999.
Derwent Abstracts, AN 1997-536794, XP-002256776, CN 1-128111, Aug. 7, 1996.
Patent Abstracts of Japan, JP 03-258726, Nov. 19, 1991.
R. Adams, et al., Journal of American Chemical Society, vol. 74, pp. 5346-5348, Preparation and Reactions of o-Hydroxycinnamic Acids and Esters, 1952.
U.S. Appl. No. 11/209,672, filed Aug. 24, 2005, Suzuki et al.
U.S. Appl. No. 11/452,374, filed Jul. 14, 2006, Suzuki et al.
U.S. Appl. No. 11/813,978, filed Jul. 13, 2007, Ochiai et al.

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