Agent for preventing and/or treating sinusitis

Details Agent for preventing and/or treating sinusitis Agent for preventing and/or treating sinusitis

2007-08-07

2007-08-07

Sheikh, Humera N (Department: 1615)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

Reexamination Certificate

active

11106662

ABSTRACT:
An agent for preventing and/or treating sinusitis, comprising, as an active ingredient, a compound of the formula (I):or a salt and/or hydrate thereof.The pranlukast hydrate is useful as an agent for preventing and/or treating sinusitis.

REFERENCES:
patent: 6194431 (2001-02-01), Rubin
patent: 6423721 (2002-07-01), Harris et al.
patent: 0641569 (1995-03-01), None
patent: WO 99/32125 (1999-07-01), None
Manabu Fujita et al., “Effects of a Specific Cysteinyl Leukotriene Antagonist, Pranlukast, on Antigen-induced Cysteinyl Leukotriene-Mediated Rhinitis in Guinea Pigs”, Jpn. J. Pharmacol., vol. 75, No. 4, (1997), pp. 347-353.
Taber's Cyclopedic Medical Dictionary, Definition of Sinusitis, p. 1804 (1993).
Kukhta, A.L. et al., “Leukotriene (LT) Pathway Modifiers: Are They the Newest Line of Therapy for Chronic Sinusitis?: Case Reports”, Journal of Allergy and Clinical Immunology, vol. 101, No. 1/2 , p. S252, Abstract (Jan. 1998).
Chambers, R.J. et al., “Development of New Chromanol Antagonists of Leukotriene D4”, Bioorganic & Medicinal Chemistry Letters, vol. 8, No. 14, 1791-1796, (Jul. 21, 1998).
Shoji Yamazaki et al., “Effects of thrombotic acid A2 and histamine on allergic rhinitis in guinea pigs,” Jpn. Pharmacol. Ther. (Medicine and Treatment), vol. 26, No. 8 (Aug. 20, 1998), pp. 1217-1227.
Manabu Fujita et al., “Immediate phase and delayed phase effects of pranlukast hydrate on antigen evoked nasal allergy model in guinea pigs,” Jpn. Pharmacol Ther. (Medicine and Treatment, vol. 25, No. 5, (1997), pp. 1379-1386.
S. Narita et al., “Effects of a cysteinyl leukotriene antagonist, ONO-1078 (pranlukast), on total airway resistance after antigen challenge in sensitized guinea pigs,” Inflamm. Res., vol. 46, No. 4 (1997), pp. 143-146.
Manabu Fujita et al., “Effects of a Specific Cysteinyl Leukotriene Antagonist, Prankukast, on Antigen-Induced Cysteinyl Leukotrience-Mediated Rhinitis in Guinea Pigs,” Jpn. J. Pharmacol., vol. 75, No. 4, (1997), pp. 347-353.
F. Takahisa et al. edit, “Merck Manual, 16thedition,” (May 1, 1995, 3rdprinting), Chapter “Sinusitis”, pp. 2243-2244.
American Academy of Allergy Asthma and Immunology 54thAnnual Meeting, Washington, D.C., Mar. 13-18, 1998, Abstracts of papers to be presented during scientific sessions.

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