Agent for potentiating nerve growth factor activity containing 1

Details Agent for potentiating nerve growth factor activity containing 1 Agent for potentiating nerve growth factor activity containing 1

1999-03-09

2000-08-15

Raymond, Richard L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514469, A61K 31445, A61K 31485, A61K 31535, A61K 3154

Patent

active

061037540

ABSTRACT:
A 1,2-ethanediol derivative represented by the general formula [I] or its salt: ##STR1## has a NGF activity-potentiating effect and is useful as a remedy for various diseases caused by degeneration of central nervous system or peripheral nervous system such as senile dementia of Alzheimer type, Huntington's chorea, various neuropathies, Riley-Day syndrome, traumatic nerve injury, amyotrophic lateral sclerosis (ALS) and the like.

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Chemical Abstracts, vol. 119, No. 9, p. 72, column 2, XP002048283; Aug. 30, 1993 S. Ono et al., "Protective Effect of R(-)-1-(Benzo[b]thiophen-5-yl)-2-[2-(N,N-diethylamino)ethoxy]ethanol hyrdochloride (T-588), a Novel Cerebral Activator, Against Experimental Cerebral Anoxia", Aug. 30, 1993.

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