Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2011-04-26
2011-04-26
Padmanabhan, Sreeni (Department: 1627)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S150000
Reexamination Certificate
active
07932276
ABSTRACT:
The present invention provides a useful and highly safe agent for the treatment of chronic obstructive pulmonary disease, which contains, as the effective ingredient, at least one compound selected from the group consisting of thiazole derivatives and salts thereof represented by the general formula (1),wherein, R1is a phenyl group which may have 1 to 3 lower alkoxy groups as the substituents on the phenyl ring; R2is a pyridyl group which may have 1 to 3 carboxyl groups as the substituents on the pyridine ring.
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Hanania, N.A. “Inflammation in COPD: Can Anything Be Done?”, Medscape, Jun. 30, 2005.
Ohnishi et al. “Generation of tumor necrosis factor alpha by human nasal epithelial cells and inhibition by fluticasone propionate” Arerugi, Oct. 1995, pp. 1216-22; abstract provided.
Cazzola et al. “Additive Effects of Salmeterol and Fluticasone or Theophylline in COPD”, Chest, 2000, vol. 118, pp. 1576-1581.
Translation of the Office Action issued in the corresponding Egyptian application.
Ikezono Katsumi
Maeda Takashi
Nagamoto Hisashi
Ohta Kazuhide
Sekiguchi Kazuo
Carter Kendra D
Finnegan Henderson Farabow Garrett & Dunner L.L.P.
Otsuka Pharmaceutical Co. Ltd.
Padmanabhan Sreeni
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