Agent and method for the prevention of metastases of malignant t

Details Agent and method for the prevention of metastases of malignant t Agent and method for the prevention of metastases of malignant t

1987-05-01

1990-08-07

Griffin, Ronald W.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

514 53, 514 62, 536 41, 536 187, 536 530, A01N 4304, C07G 300, C07G 0000, C07H 504

Patent

active

049468308

ABSTRACT:
Agents and methods for the prevention of metastases of malignant tumors use the monosaccharides which are specific for organ cell lectins and/or glycoconjugates containing these monosaccharides, and more specifically, .beta.-D-galactose and/or glycoconjugates containing terminal .beta.-D-galactose moieties.

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Uhlenbruck et al., Experientia 43(1987), Birkhauser Verlog, CH-4010 Basel/Switzerland.
Schirrmacher et al., Clin. Expl. Metastases, 1988, vol. 6, No. 2, 115-120.
Rozkowski et al., Experientia (in press), "Blocking of Lectin-Like Adhesion Molecules on Pulmonary Cells Inhibits Lung Sarcoma L-1 Col. in BALB/c-mice".
Pulverer et al. J. Cancer Res Clin. Onocol., (1988) 114:217-220.
Roszkowski et al. Experientia, 45 (1989) pp. 584-588.

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