Agaricus extract for preventing the induction or metastasis...

Drug – bio-affecting and body treating compositions – Extract or material containing or obtained from a...

Reexamination Certificate

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Reexamination Certificate

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07611715

ABSTRACT:
A foodstuff capable of preventing the induction or metastasis of cancer is provided. In particular, anAgaricus blazeiMurill extract comprising an ingredient capable of preventing the induction or metastasis of cancer is provided. The ingredient can be a chromatographic main elute fraction of 100 to 2000 molecular weight, obtained by the steps of extracting the fruit body ofAgaricus blazeiMurill with hot water, dialyzing the resultant extract, and subjecting the thus obtained dialysis external fluid to chromatography. Alternatively, the ingredient can be a dialysis external fluid obtained by the steps of extracting the fruit body ofAgaricus blazeiMurill with hot water, adding ethanol to the resultant extract to thereby obtain precipitates, dissolving the precipitates in water, and dialyzing the solution.

REFERENCES:
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patent: 2003128561 (2003-05-01), None
See et al. (Immunology Investigations (May 2002), vol. 31, No. 2, pp. 137-153).
Yu et al. (Eur. J. Biochem. (2000), vol. 267, pp. 2122-2126).
Ito (Biotherapy (2000), vol. 14, No. 10, pp. 1009-1015—abstract).
International Search Report (ISR) dated Aug. 19, 2003 from PCT/JP03/008157.
Kadosawa, et al., “Clinical Efficacy ofAgaricus blazeiMurill and/or Shark Cartilage in Dogs and Cats with Tumors”,Jpn. J. Small Anim. Pract., 20(2):101-109, 2001.

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