AFLP-based method for integrating physical and genetic maps

Details AFLP-based method for integrating physical and genetic maps AFLP-based method for integrating physical and genetic maps

2011-06-28

2011-06-28

Zhou, Shubo (Joe) (Department: 1631)

Data processing: measuring, calibrating, or testing

Measurement system in a specific environment

Biological or biochemical

C435S006120, C702S020000, C703S011000

Reexamination Certificate

active

07970548

ABSTRACT:
The invention pertains to a method for the integration of physical and genetic maps and markers. The method is based on the use of AFLP fingerprinting with primers of varying selectivity on a library of artificial chromosomes such as a BAC library. The fingerprinting is performed on the individual BACs and on the pools of BACs. Subsequent alignment generates a contig and provides the integration of physical and genetic markers resulting in the integration of the physical and genetic map.

REFERENCES:
Klein et al., Genome Research, vol. 10, pp. 789-807, 2000.

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