Liquid purification or separation – Processes – Liquid/liquid solvent or colloidal extraction or diffusing...
Patent
1996-06-20
1999-02-09
Kim, John
Liquid purification or separation
Processes
Liquid/liquid solvent or colloidal extraction or diffusing...
21032179, 2103218, 21032188, 21032189, 210434, 21050023, 210650, 210651, 435178, 435179, 435180, 435181, B01D 6100, B01D 6302, A61M 134
Patent
active
058689362
ABSTRACT:
The present invention provides an improved affinity membrane device and method for the effective removal of target molecules in plasma. The affinity membrane device is designed for use in an extracorporeal blood circuit and can be employed concurrently with other therapeutic processes for the purification of blood. The device of the present invention consists of hollow fiber membranes having specified dimensions and transfer properties, ligand immobilized to the pore surface of the hollow fibers, and a housing to encase the hollow fibers and allow appropriate entry and exit of the blood. In a preferred embodiment, specific immobilization chemistries are utilized to attach the ligands to the hollow fibers for optimal function.
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Kunas Gretchen A.
Ofsthun Norma J.
Soltys Paul J.
Barrett Robert M.
Baxter International Inc.
Borecki Thomas S.
Kim John
Mattenson Charles R.
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