Affinity matrices of modified polysaccharide supports

Details Affinity matrices of modified polysaccharide supports Affinity matrices of modified polysaccharide supports

1989-02-16

1991-10-22

Nutter, Nathan M.

Synthetic resins or natural rubbers -- part of the class 520 ser

Synthetic resins

Mixing of two or more solid polymers; mixing of solid...

525 542, 525 5421, 530412, 530413, 210656, 2101982, 2105021, 422 59, 422 70, 422 89, 435 91, 435180, C08H 500, A61K 3704, B01J 2000, C07K 320

Patent

active

050596543

ABSTRACT:
The invention is directed to a modified polysaccharide material which comprises: (1) polysaccharide covalently bonded to a synthetic polymer; (2) the synthetic polymer being made from (a) a polymerizable compound which is capable of being covalently coupled directly or indirectly to said polysaccharide, and (b) one or more polymerizable compounds containing (i) a chemical group capable of causing the covalent coupling of the compound (b) to an affinity ligand or a biologically active molecule or (ii) a hydrophobic compound.
The invention is also directed to devices for the chromatographic separation of at least two components of a mixture comprising the modified polysaccharide material of the invention, wherein the device is configured for radial or tangential flow.

REFERENCES:
patent: 3891580 (1975-06-01), Morris et al.
patent: 4210723 (1980-07-01), Dorman et al.
patent: 4224439 (1980-09-01), Ayers et al.
patent: 4352884 (1982-10-01), Nakashima et al.
patent: 4384957 (1983-05-01), Crowder, III et al.
patent: 4385991 (1983-05-01), Rosevear et al.
patent: 4421650 (1983-12-01), Nagasawa et al.
patent: 4743373 (1988-05-01), Rai et al.

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