Affinity chromatography matrix with built-in reaction indicator

Details Affinity chromatography matrix with built-in reaction indicator Affinity chromatography matrix with built-in reaction indicator

1984-03-02

1985-06-18

Adee, John

Liquid purification or separation

Processes

Liquid/liquid solvent or colloidal extraction or diffusing...

210656, 2105021, 502157, 502402, 502403, B01D 1508

Patent

active

045239975

ABSTRACT:
p-Nitrophenylester of succinoylaminopropyl silica gel is useful as an affinity matrix for reacting with ligand for use in affinity chromatography. The affinity matrix, upon reaction with a ligand, releases one molecule of p-nitrophenolate ion for every molecule of ligand that reacts and the solution turns yellow as the reaction occurs.

REFERENCES:
patent: 3892678 (1975-07-01), Halasz
patent: 4212905 (1980-07-01), Tsibris
patent: 4213860 (1980-07-01), Tsibris
patent: 4334972 (1982-06-01), Soderberg

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