Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1998-04-15
1999-07-13
Bawa, Raj
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 46, 514937, 514826, A61K 912
Patent
active
059223065
ABSTRACT:
A pharmaceutical formulation comprising (i) one or more particulate medicaments, and (ii) 1,1,1,2-tetrafluoroethane as propellant, which formulation contains less than 0.0001% w/w surfactant based upon the weight of medicament, particulate medicament being present in an amount from 0.005 to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns, with the proviso that said medicament is other than salmeterol, salbutamol, fluticasone propionate, beclomethasone dipropionate or a physiologically acceptable salt or solvate thereof and with the proviso that when said formulation consists of betamethasone, ergotamine tartrate or sodium cromoglycate and 1,1,1,2-tetrafluoroethane the weight to weight ratio of medicament to propellant is other than 69:7900 or 0.866% w/w.
REFERENCES:
patent: 2868691 (1959-01-01), Porush et al.
patent: 2885427 (1959-05-01), Rob et al.
patent: 3014844 (1961-12-01), Thiel et al.
patent: 3219533 (1965-11-01), Mullins
patent: 3320125 (1967-05-01), Grim
patent: 3809294 (1974-05-01), Torgeson
patent: 3897779 (1975-08-01), Hansen
patent: 4174295 (1979-11-01), Bargigia et al.
patent: 4405598 (1983-09-01), Brown
patent: 5653962 (1997-08-01), Akehurst et al.
patent: 5674471 (1997-10-01), Akehurst et al.
Oberholz, Frankfurter Allegmeine Zeitung, Oct. 1989, vol. 25, No. 207, p. 7.
Dalby et al., Pharmaceutical Technology, Mar. 1990, vol. 14, No. 3, pp. 26-33.
Amzacort.TM. carton, William H. Rorer, Inc., Fort Washington, Pennsylvania, USA 19034, 1986.
Pharmaceutical Journal, Sep. 29, 1990, vol. 245, pp. 428-429,.
The Theory and Practice of Industrial Pharmacy, 2nd Ed., 1976 (Philadelphia, PA: Lea and Febiger), pp. 270 and 276-278.
Handbook of Aerosol Technology, 2nd Edition, 1979 (New York, New York: Van Nostrand Reinhold Company), pp. 30, 32, 33, 166, 167, 232, 233.
U.S. Senate Hearings, May 12-14, 1987, 343-347, 437 (U.S. Government Printing Office, Washington, D.C., 1987), CIS:1987-S321-26.
Hagers Handbook of Pharmaceutical Practice, 1971, pp. 342-354 (Berlin: Springer-Verlag).
Akehurst Rachel Ann
Taylor Anthony James
Wyatt David Andrew
Bawa Raj
Glaxo Group Limited
LandOfFree
Aerosol formulations containing P134a and particulate medicament does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Aerosol formulations containing P134a and particulate medicament, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Aerosol formulations containing P134a and particulate medicament will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2273256