Aerosol formulations containing P134A and/or P227 and particulat

Details Aerosol formulations containing P134A and/or P227 and particulat Aerosol formulations containing P134A and/or P227 and particulat

1998-04-06

1999-06-29

Bawa, Raj

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424 46, 514937, A61K 912

Patent

active

059165405

ABSTRACT:
A pharmaceutical aerosol formulation comprising (i) particulate medicament, (ii) 1,1,1,2-tetrafluoroethane, 1,1,1,2,3,3,3,-heptafluoro-n-propane or a mixture thereof as propellant, and (iii) 0.01 to 5% w/w based upon the propellant of a polar cosolvent, the particulate medicament being present in an amount from 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns, and which formulation contains less than 0.0001% w/w surfactant based upon the weight of medicament.

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