Aerosol filling method

Details Aerosol filling method Aerosol filling method

1993-02-24

1994-01-04

Cusick, Ernest G.

Fluent material handling, with receiver or receiver coacting mea

Processes

Filling dispensers

141 20, 141 82, 141 11, B65B 104, B65B 304

Patent

active

052752127

ABSTRACT:
A process for preparing a medicinal aerosol formulation containing a propellant that is gaseous at standard temperature and pressure and filling the formulation into a metered dose aerosol canister. The process involves mixing the propellant and the drug at ambient temperature and under pressure sufficient to liquify the propellant to afford a formulation. The formulation is cooled to a temperature sufficiently low to liquify the propellant at atmospheric pressure and filled into aerosol canisters in an environment of controlled humidity. An aerosol valve is placed on each aerosol canister and the finished canisters are removed from the controlled environment.

REFERENCES:
patent: 3502118 (1970-03-01), Assalit
patent: 4921020 (1990-05-01), Pamper

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