Aerosol compositions

Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid

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424 43, 424 47, A61L 904

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active

052099210

ABSTRACT:
Aerosol compositions for topical application, conferring a cooling effect on the body and suitable for use in the alleviation of pain, such as muscular or rheumatic pain, which compositions do not contain environmentally unacceptable chlorofluorocarbons but satisfy safety guidelines on flammability, and comprise an organic substance, other than a chlorofluorocarbon, having a boiling point within the range of from 10.degree. to 40.degree. C. and an organic substance, other than a chlorofluorocarbon, having a boiling point within the range of from -45.degree. to -10.degree. C., in a ratio of from 3 to 7 parts by weight of the higher boiling component (serving primarily as a coolant) per part by weight of the lower boiling component (serving primarily as a propellant).

REFERENCES:
patent: 3912667 (1975-10-01), Spitzer et al.
patent: 4134968 (1979-01-01), Stebles
patent: 4243548 (1981-01-01), Heeb et al.
patent: 4450151 (1984-05-01), Shinozawa
patent: 4716032 (1987-12-01), Westfall et al.
Patent Abstracts of Japan, vol. 11, No. 214 (C-434) (2661), 1987.
Patent Abstracts of Japan, vol. 6, No. 11 (C-88) (889), 1982.
Patent Abstracts of Japan, vol. 11, No. 206 (C-433) (2653), 1987.
Chemie-Lexikon, 8th Edition, vol. 4, p. 2579, 1985.
Seifen-Ole-Fette-Wachse, vol. 111, pp. 179-180, 1985.

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