Aerosol composition comprising formoterol

Details Aerosol composition comprising formoterol Aerosol composition comprising formoterol

2005-05-03

2005-05-03

Hartley, Michael G. (Department: 1616)

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

C424S046000, C424S489000, C424S443000, C424S435000, C514S826000

Reexamination Certificate

active

06887459

ABSTRACT:
The use of a dry powder comprising (A) formoterol, or a pharmaceutically acceptable salt or solvate thereof, or solvate of said salt, and (B) a pharmaceutically acceptable particulate diluent or carrier in an amount of from 400 μg to 5000 μg per μg of (A) for the preparation of an inhalable medicament for the treatment of chronic obstructive pulmonary disease.

REFERENCES:
patent: 5795564 (1998-08-01), Aberg et al.
patent: 6045828 (2000-04-01), Bystrom et al.
patent: WO 9311773 (1993-06-01), None
patent: WO 9831351 (1998-07-01), None
patent: WO 9915182 (1999-04-01), None
patent: WO 0047200 (2000-08-01), None
Maesen FPV et al., “Formoterol as dry Powder Inhalation”, Chest, Park Ridge, Il, US vol. 101, No. 5, 1992, pp. 1376-1381, XP000911155.
Barnes, P J: “Chronic obstructive pulmonary disease: new opportunities for drug development”, Trends in Phamacological Sciences, Elsevier Trends Journal, Cambridge, GB, vol. 19, No. 10, Oct. 1998, pp. 415-423.
Maesen B L P et al., “Effects of formoterol in apparently poorly reversible chronic obstructive pulmonary disease”, European Respiratory Journal, vol. 13, No. 5, May 1999, pp. 1103-1108, XP001020413, ISSN: 0903-1936 the whole document.
Sichletidis et al., Int. J. Clin. Pract., vol. 53, No. 3., pp. 185-188, “Bronchodilatory Responses to Formoterol, Ipratropium, and Their Combination in Patients with Stable COPD” (1999).
British National Formulatory, British Medical Association & Royal Pharmaceutical Society, September, No. 38, see Section 3.1.3, pp. 131-132 (1999).
Reynolds (ed), “Martindale. The Extra Pharmacopoeia”, 31st edition, Royal Pharmaceutical Society, p. 1575 (re. eformoterol fumarate), p. 1567 (re. chronic obstructive pulmonary disease) and pp. 1591-1593 (re.salbutamol), 1996.

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