Aerosol carriers

Details Aerosol carriers Aerosol carriers

1991-09-20

1993-10-19

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424434, 424435, 424489, 424493, 514169, 514456, A61K 914

Patent

active

052543307

ABSTRACT:
Pharmaceutical excipients useful in dry powder inhalents comprise particles having a rugosity (measured by air permeametry) of less than 1.75. The use of these carriers increases the amount of drug injested by the patient using a dry powder inhaler. The preferred excipients are crystalline sugars such as lactose which may conveniently be prepared by controlled crystallisation from an aqueous medium.

REFERENCES:
patent: 4199578 (1980-04-01), Stevenson
patent: 4232002 (1980-11-01), Nogrady
patent: 4349542 (1982-09-01), Staniforth
patent: 4409237 (1983-10-01), Cairns et al.
patent: 4613500 (1986-09-01), Suzuki
patent: 4847091 (1989-07-01), Illum
patent: 4940556 (1990-07-01), MacFarlane

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