Aerosol carriers

Details Aerosol carriers Aerosol carriers

1992-04-27

1994-12-27

Kishore, Gollamudi

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424 46, 424434, 424435, 424489, 514 23, 514 53, 514 54, 514 55, 514 56, 514 57, 514 58, 514 59, 514 60, 514 61, 536 111, 127 58, A61K 914

Patent

active

053763866

ABSTRACT:
Pharmaceutical excipients useful in dry powder inhalents comprise particles having a rugosity (measured by air permeametry) of less than 1.75. The use of these carriers increases the amount of drug injested by the patient using a dry powder inhaler. The preferred excipients are crystalline sugars such as lactose which may conveniently be prepared by controlled crystallisation from an aqueous medium.

REFERENCES:
patent: 4199578 (1980-04-01), Stevenson
patent: 4232002 (1980-11-01), Nogrady
patent: 4349542 (1982-09-01), Staniforth
patent: 4409237 (1983-10-01), Cairns
patent: 4590206 (1986-05-01), Forrester
patent: 4613500 (1986-09-01), Suzuki et al.
patent: 4847091 (1989-07-01), Illum
patent: 4940556 (1990-07-01), MacFarlane et al.
patent: 5198226 (1993-03-01), MacFarlane et al.
patent: 5254330 (1993-10-01), Ganderson et al.

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