Drug – bio-affecting and body treating compositions – Effervescent or pressurized fluid containing – Organic pressurized fluid
Patent
1978-12-18
1979-11-13
Fagelson, Anna P.
Drug, bio-affecting and body treating compositions
Effervescent or pressurized fluid containing
Organic pressurized fluid
424 45, 424 46, 424 65, 424 66, 424 67, 424 68, A61K 732, A61K 734, A61K 738
Patent
active
041743865
ABSTRACT:
Aerosol antiperspirant compositions are provided that are highly concentrated with respect to the active astringent salt, and capable of being dispensed from aerosol containers of the foam type at a low delivery rate, comprising, in combination, an astringent salt in an amount within the range from about 8 to about 30%; a liquefied propellant, or a mixture of liquefied propellants, each with a vapor pressure at 21.degree. C. of at least 2.4 atmospheres absolute, having a low molecular weight, in an amount of at least 0.15 mole per atmosphere absolute pressure in the container at 21.degree. C. per 100 g of composition; a nonvolatile miscible organic liquid in an amount within the range from about 0.1 to 30% by weight of the composition; a bulking agent in an amount within the range from about 0.1 to about 5% by weight of the composition; and a solid aliphatic carboxylic acid having from about fourteen to about twenty-two carbon atoms in a straight chain and in an amount within the range from about 0.1 to about 5% by weight of the composition to enhance adherence of the antiperspirant salt to the skin.
REFERENCES:
patent: 3725540 (1973-04-01), Wahl
patent: 3903258 (1975-09-01), Siegal
patent: 3929986 (1975-12-01), Bouillon
patent: 3953450 (1976-04-01), Bouillon
patent: 3956352 (1976-05-01), Bouillon
patent: 3963833 (1976-06-01), DeSalva
patent: 3968203 (1976-07-01), Spitzer
patent: 3974270 (1976-08-01), Kenkare
patent: 4053581 (1977-10-01), Pader
patent: 4065564 (1977-12-01), Miles
Sagarin, Cos., Sci & Tech. Intersci., N.Y. 1957, pp. 717-739.
Marra Dorothea C.
Osipow Lloyd I.
Small Marvin
Spitzer Joseph G.
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