Advanced route for the synthesis of cPLA2 inhibitors

Details Advanced route for the synthesis of cPLA2 inhibitors Advanced route for the synthesis of cPLA2 inhibitors

2005-05-10

2005-05-10

O'Sullivan, Peter (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C548S506000, C548S507000, C558S413000, C564S089000, C564S092000, C564S097000

Reexamination Certificate

active

06891065

ABSTRACT:
A process for making a compound of formula (I)in which process the compound HC≡C—(CH2)n—NH2is reacted with the compound R1—SO2Cl to produce an intermediate compound, which intermediate compound is then reacted with the compound of formulato produce the compound of formula (I), and compounds produced by the process of this invention. The terms R1, R2, R3, R4and n have the definitions set forth in the specification.

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