Advanced glycosylation endproducts and methods of use therefor

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530331, 530345, 514 17, 514 18, 562560, 562562, A61K 3805

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active

058114017

ABSTRACT:
The present invention relates to advaced glycosylation endproducts formed by the reaction of arginine-lysine or lysine-arginine dipeptides, optionally as part of a larger protein or amino-containing-biomolecule, with reducing sugars. These AGEs can be used in various diagnostic and therapeutic methods.

REFERENCES:
patent: 5214138 (1993-05-01), Monnie
patent: 5238963 (1993-08-01), Cerami
patent: 5334617 (1994-08-01), Ulrich
patent: 5480807 (1996-01-01), Monnie
patent: 5624804 (1997-04-01), Bucala
Araki et al. (1992) J. Biol. Chem. 267:10211-4.
Brownlee et al. (1983) J. Exp. Med. 158:1739-44.
Bucala et al. (1993) Proc. Natl. Acad. Sci. USA 90:6434-8.
Cohen et al. (1994) Kidney International 45:1673-9.
Harris et al. (1993) TIBTECH 11:42-46.
Horiuchi et al. (1991) J. Biol. Chem. 266:7329-32.
Kohn et al. (1984) Diabetes 33:57-9.
Makita et al. (1992) J. Biol. Chem. 267: 5133-8.
Makita et al. (1992) Science 258:651-3.
Nakayama et al. (1989) Biochem. Biophys. Res. Commun. 162:740-5.
Al-Abed, Bioorganic Med Chem Lett. 5, 2929, 1995.

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