Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1996-09-10
1999-11-16
Tsang, Cecilia J.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514345, 514351, 514247, 514256, 514276, 514 23, 514 25, A61K 3100
Patent
active
059858575
ABSTRACT:
The instant invention provides compositions and methods for modeling post-Amadori AGE formation and the identification and characterization of effective inhibitors of post-Amadori AGE formation, and such identified inhibitor compositions.
REFERENCES:
patent: 4665192 (1987-05-01), Cerami
patent: 4758583 (1988-07-01), Cerami et al.
patent: 4908446 (1990-03-01), Ulrich et al.
patent: 4983604 (1991-01-01), Ulrich et al.
patent: 5017696 (1991-05-01), Farmar et al.
patent: 5100919 (1992-03-01), Ulrich et al.
patent: 5106877 (1992-04-01), Ulrich et al.
patent: 5128360 (1992-07-01), Cerami et al.
patent: 5130324 (1992-07-01), Ulrich et al.
patent: 5130337 (1992-07-01), Ulrich et al.
patent: 5137916 (1992-08-01), Ulrich et al.
patent: 5140048 (1992-08-01), Ulrich et al.
patent: 5175192 (1992-12-01), Ulrich et al.
patent: 5218001 (1993-06-01), Ulrich et al.
patent: 5221683 (1993-06-01), Ulrich et al.
patent: 5238963 (1993-08-01), Cerami et al.
patent: 5242593 (1993-09-01), Ulrich et al.
patent: 5254572 (1993-10-01), Serfontein
patent: 5258381 (1993-11-01), Ulrich et al.
patent: 5262152 (1993-11-01), Ulrich et al.
patent: 5272165 (1993-12-01), Ulrich et al.
patent: 5272176 (1993-12-01), Ulrich et al.
patent: 5288716 (1994-02-01), Speck
patent: 5318982 (1994-06-01), Ulrich et al.
patent: 5334617 (1994-08-01), Ulrich et al.
patent: 5358960 (1994-10-01), Ulrich et al.
Brownlee et al., 1983, Covalent Attachment of Soluble Proteins by Nonenzymatically Glycosylated Collagen, J. Exp. Med. 158:1739.
Brownlee et al., 1988, Advanced Glycosylation End Products in Tissue and the Biochemical Basis of Diabetic Complications, New Eng. J. Med. 318:1315.
Pongor et al., 1984, Aging of Protiens: Isolation and identification of a fluorescent chromophore from the reaction of polypeptides with glucose, PNAS 81:2684.
Khatami et al., 1988, Inhibitory effects of pyridoxal phosphate, ascorbate and aminoguanidine on nonenzymatic glycosylation, Life Sciences 43:1725.
Brownlee 1989, "Pharmacological modulation of the advanced glycosylation reaction" in The Maillard Reaction in Aging, Diabetes, and Nutrition, pp. 235-248 (A.R. Liss, Inc.).
Brownlee et al., 1986, Aminoguanidine Prevents Diabetes-Induced Arterial Wall Protein Cross-linking, Science 232:1629.
Hayakawa et al., 1991, The In Vitro and In Vivo inhibition of Protein Glycosylation and Diabetic Vascular Basement Membrane Thickening by Pyridoxal-5'-Phosphate, J. Nutr. Sci. Vitaminol. 37:149.
Ganea et al., 1994, Binding of glucose, galactose and pyridoxal phosphate to lens crystallins, Biochem. Biophys, Acta 1226:286.
HCAPLUS AN 1978: 20319, Kjoesen et al., Am. J. Clin. Nutr., 30(10), 1591-6, 1977.
HCAPLUS 1994: 260575, Nakamura et al., Nippon Kagaku Kaishi, 3, 307-16.
HCAPLUS 1984: 185545, Zimmer et al., Adv. Exp. Med. Biol., 165, 477-81.
Shepard et al., Biochemical Archives, vol. 1, pp. 143-151, 1985.
Booth Aaron Ashley
Hudson Billy G.
Khalifah Raja Gabriel
Todd Parvin
Delacroix-Muirheid C.
Harper David
Kansas University Medical Center
Tsang Cecilia J.
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