Advanced characterization of contrast agents with ultrasound

Surgery – Diagnostic testing – Detecting nuclear – electromagnetic – or ultrasonic radiation

Reexamination Certificate

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C600S437000, C600S443000, C382S128000

Reexamination Certificate

active

07998076

ABSTRACT:
Contrast agents are characterized with ultrasound. Flowing or unbound contrast agents are distinguished automatically from bound or relatively stationary contrast agents. The bound or relatively stationary contrast agents are highlighted on a display. A processor distinguishes different types of contrast agents or contrast agents in different binding states with relative signal strength or velocity. Attached contrast agents are differentiated from phagocytosed contrast agents. Monitoring absolute signal strength as a function of time may indicate binding. Any one or more of these features may be used.

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