Adult-onset diabetes treatment method

Details Adult-onset diabetes treatment method Adult-onset diabetes treatment method

1997-02-11

1998-12-22

Witz, Jean C.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

A01N 6500

Patent

active

058515313

ABSTRACT:
Methods for treating adult-onset diabetes and inducing weight loss are presented. An effective amount of pokeweed mitogen containing a chloroform precipitable fraction is administered to a mammal to treat adult-onset diabetes. Weight loss is induced by administering effective amount of pokeweed mitogen containing a chloroform precipitable fraction or Momordica lectin to induce a decline in food intake in a mammal.

REFERENCES:
patent: 4985248 (1991-01-01), Liu
Bardocz et al., British Journal of Nutrition, 76, 613-626(1996).
Waxdal, M. "Isolation, characterization and biological activities of five mitogens from pokeweed," Biochemistry (1974) 13(18): 3671-77.
Ng et al. "Isolation and characterization of a galactose binding lectin with insulinomimetic activities," Int. J. Peptide Res. (1986) 28:163-172.
Sigma Catalog (1993), p. 1726.
Newsholme et al. "Biochemistry for the Medical Sciences", (1983) (John Wiley: London) p. 706.
Akhtar "Trial of Momordica Charantia Linn (Karela) Powder in Patients with Maturity-Onset Diabetes", J. Pakistan Med. Assn. (1982) 32(4): 106-7.

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