Adsorption method and ligands

Details Adsorption method and ligands Adsorption method and ligands

2007-05-08

2007-05-08

Hopkins, Robert (Department: 1724)

Liquid purification or separation

Processes

Ion exchange or selective sorption

C210S681000

Reexamination Certificate

active

10312054

ABSTRACT:
The invention relates to a method for removing a positively charged substance from an aqueous liquid (I) by contacting the liquid with a cation-exchanger (1), possibly followed by a subsequent desorption of said substance. The cation-exchanger is selected to be capable of (a) binding to said substance by cation-exchange in an aqueous liquid reference (II) at an ionic strength corresponding to 0.3 M NaCl and (b) permitting a break through capacity for said substance3200%, such as3300% or3500%, of the break-through capacity of said substance for a reference cation-exchanger (2) containing sulphopropyl groups —CH2CH2CH2SO2O—. The cation exchange ligands have an at least bimodal function by comprising a cation exchanging group and a separate hydrogen-bonding atom. The invention also relates to a method for testing the appropriateness of a cation-exchanger for removing a substance from a liquid and novel cation exchangers.

REFERENCES:
patent: 5045190 (1991-09-01), Carbonell et al.
patent: 2 050 192 (1981-01-01), None
patent: WO98/08603 (1998-03-01), None
patent: WO99/65607 (1999-12-01), None
patent: WO01/38227 (2001-05-01), None
Thoemmes Joerg, “Investigations on Protein Adsorption to Agarose-Dextran Composite Media” Biotechnology and Bioengineering vol. 62, No. 3, Feb. 5, 1999 pp. 358-362.

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