Adsorption chromatography

Liquid purification or separation – Processes – Chromatography

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

2101982, 530413, 530417, B01D 1508

Patent

active

060276509

ABSTRACT:
The present invention relates to methods useful for purifying materials using adsorbent chromatography, preferably in an expanded bed or packed bed configuration without the need to use a moving packed bed adapter, thereby improving elution characteristics for the sample molecule of interest.

REFERENCES:
patent: 4411789 (1983-10-01), Liburdy
patent: 4675113 (1987-06-01), Graves
patent: 5084184 (1992-01-01), Burns
patent: 5522993 (1996-06-01), Carlsson
Carter et al., "Humanization of an anti-p185.sup.HER2 antibody for human cancer therapy" Proc. Natl. Acad. Sci. 89:4285-4289 (1992).
Chang and Chase, "Ion exchange purification of G6PDH From Unclarified Yeast Cell Homogenates Using Expanded Bed Adsorption" Biotechnology and Bioengineering 49:204-216 (1996).
Chang et al., "Development of an expanded bed technique for an affinity purification of G6PDH from unclarified yeast cell homogenates" Biotechnology and Bioengineering 48:355-366 (1995).
Draeger et al., "Liquid fluidized bed adsorption of protein in the presence of cells" Bioseparation 2(2):67-80 (1991).
Fischer et al., "Reduction of Graft Failure by a Monoclonal Antibody (Anti-LFA-1 CD11a) After HLA Nonidentical Bone Marrow Transplantation in Children with Immunodeficiencies, Osteopetrosis, and Fanconi's Anemia" Blood 77(2):249-256 (Jan. 15, 1991).
Hourmant et al., "Administration of an Anti-CD11a Monoclonal Antibody in Recipients of Kidney Transplantation" Transplantation 58(3):377-380 (Aug. 1994).
Kim et al., "The Vascular Endothelial Growth Factor Proteins: Identification of Biologically Relevant Regions by Neutralizing Monoclonal Antibodies" Growth factors 7(1):53-64 (1992).
Liu et al., "Production of a Mouse-Human Chimeric Monoclonal Antibody to CD20 with Potent Fc-Dependent Biologic Activity" J. Immunol. 139:3521-3526 (1987).
Maloney et al., "Phase I Clinical Trial Using Escalating Single-Dose Infusion of Chimeric Anti-CD20 Monoclonal Antibody (IDEC-C2B8) in Patients With Recurrent B-Cell Lymphoma" Blood 84:2457-2466 (1994).
Pharmacia Biotech Expanded Bed Adsorption: Principles and Methods (ISBN 91-630-5519-8), AA edition pps. 1-160 undated.
Presta et al., "Humanization of an Antibody Directed Against IgE" J. Immunol. 151(5):2623-2632 (Sep. 1, 1993).
Scopes, R., "Separation in Solution" Protein Purification: Principles and Practice, Chapter 8, pps. 242-249 (1994).
St. John et al., "Immunologic Therapy for ARDS, Septic Shock, and Multiple-Organ Failure" Chest 103:932-943 (1993).
Stoppa et al., "Anti-LFA1 Monoclonal Antibody (25.3) for Treatment of Steroid-resistant Grade III-IV Acute Graft-versus-host Disease" Transplant International 4:3-7 (1991).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Adsorption chromatography does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adsorption chromatography, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adsorption chromatography will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-517652

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.