Adriamycins, process for their preparation and uses thereof

Details Adriamycins, process for their preparation and uses thereof Adriamycins, process for their preparation and uses thereof

1977-08-11

1978-07-04

Love, Ethel G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D31710

Patent

active

040987981

ABSTRACT:
The known antibiotics adriamycin and its .beta.-anomer, and the novel compounds, 4'-epiadriamycin (both .alpha.- and .beta.-anomers) are prepared by condensing a novel, reactive protected derivative of adriamycinone with reactive intermediates which are 1-halo-2,3,6-trideoxy-3-trifluoroacetamido-4-trifluoroacetoxy-.alpha.-L-ly xo (or arabino) hexopyranoses.

REFERENCES:
patent: 3651090 (1972-03-01), Hardie et al.

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