Adrenocorticotropin-lipotropin precursor gene

Chemistry: molecular biology and microbiology – Miscellaneous

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435 68, 435 91, 435172, 435253, C12N 100

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active

043224997

ABSTRACT:
A technique suitable for cloning a cDNA having a base sequence coding for the ACTH/LPH precursor is disclosed. The invention is exemplified by the cloning of a cDNA fragment comprising a base sequence coding for the endorphin region. The fragment, hereinafter termed the endorphin gene cDNA sequence, was obtained from cultured mouse pituitary tumor cells known to produce the ACTH/LPH precursor protein.

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