Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1981-07-29
1982-05-11
Love, Ethel G.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D31710
Patent
active
043292895
ABSTRACT:
There are disclosed compounds of the formula ##STR1## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n-- wherein n is 2 to 20, ##STR2## and R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy, and ##STR3## wherein R.sub.1 is selected from the group consisting of lower alkyl; R.sub.8 is selected from the group consisting of --O--(CH.sub.2).sub.n-- wherein n is 2 to 20, ##STR4## and R.sub.6 is selected from the group consisting of hydrogen or lower alkoxy and racemates thereof.
There are also disclosed processes and intermediates utilized to produce the end products.
The end products have utility as agents exhibiting both .alpha. and selective .beta. adrenergic blocking action.
REFERENCES:
Chem. Abstracts: 92: P94434u.
Chem. Abstracts 48: P5227e.
Fahrenholtz Kenneth E.
Guthrie Robert W.
Kierstead Richard W.
Tilley Jefferson W.
Hoffman Frank P.
Hoffmann-La Roche Inc.
Leon Bernard S.
Love Ethel G.
Saxe Jon S.
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