Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues
Reexamination Certificate
1997-03-07
2009-08-04
Borin, Michael (Department: 1631)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
C536S023100, C536S024100, C536S024300, C536S024310, C536S024320, C536S024330, C536S025300, C514S002600, C514S04400A
Reexamination Certificate
active
07569659
ABSTRACT:
The invention concerns compositions comprising a nucleic acid mimic. The compositions may be used in the diagnosis and treatment of diseases amenable through modulation of nucleic acids which encode proteins that are implicated in disease states. In accordance with preferred embodiments, mimics are comprised of non-naturally occurring backbones to which are appended modified heterocyclic bases. Such bases preferably have sterically bulky substituents 1, 2, or 3 atoms removed from the sites of attachment to the backbone.
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Christensen Leif
Hansen Henrik Frydenlund
Nielsen Peter E.
Borin Michael
Isis Patent Department
Nielsen Peter E.
Woodcock & Washburn LLP
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