Administration of a 27-hydroxycholesterol or related compound or

Details Administration of a 27-hydroxycholesterol or related compound or Administration of a 27-hydroxycholesterol or related compound or

1993-11-30

1994-12-27

Richter, Johann

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Cyclopentanohydrophenanthrene ring system doai

514178, 514181, 514182, A61K 31575

Patent

active

053766520

ABSTRACT:
A method for preventing or reducing restenosis wherein a 27-hydroxycholesterol or a 25,26 and/or 27-aminocholesterol, or a sterol 27-hydroxylase stimulant is administered in a restenosis preventing and/or reducing amount.

REFERENCES:
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patent: 4939134 (1990-07-01), Javitt et al.
Zhou, et al., Proc. Soc. Exp. Biol. Exp. Biol. Med., 202:75-80 (1993).
Nassem, et al., Biochem. Internat., 14:71-84 (1987).
Baranowski, et al., Atherosclerosis, 41:255-260 (1982).
Kandutsch, et al., Science, 201, 498 (1978).
DeCaprio, et al., Journal of Lipid Research, vol. 33, pp. 441-443 (1992).

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