Adjuvants and copolymer compositions

Drug – bio-affecting and body treating compositions – Nonspecific immunoeffector – per se ; or nonspecific... – Synthetic polymer or copolymer

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C424S278100, C424S283100

Reexamination Certificate

active

06844001

ABSTRACT:
The present invention comprises novel polyoxyethylene/polyoxypropylene block copolymer compositions and compounds. The compositions comprise block copolymers that are high molecular weight molecules, and are useful in gene therapy methods.

REFERENCES:
patent: 2674619 (1954-04-01), Lundsted
patent: 3393243 (1968-07-01), Cuscurida
patent: 4764567 (1988-08-01), Ott
patent: 4772466 (1988-09-01), Allison et al.
patent: 4902834 (1990-02-01), Otten et al.
patent: 5313000 (1994-05-01), Stewart
patent: 5523492 (1996-06-01), Emanuele et al.
patent: 5554372 (1996-09-01), Hunter
patent: 5567859 (1996-10-01), Emanuele et al.
patent: 5674911 (1997-10-01), Emanuele et al.
patent: 0121752 (1984-10-01), None
patent: 0135376 (1985-03-01), None
patent: 0 283148 (1988-09-01), None
patent: WO 9015092 (1990-12-01), None
patent: WO 9216484 (1992-10-01), None
patent: WO 9510265 (1995-04-01), None
Aida, et al., “Synthesis of Propylene Oxide-Ethylene Oxide Block Copolymers with Controlled Molecular Weight, Using Metalloporphyrin as a Catalyst,”Makromol. Chem. Rapid Comm., vol. 1, pp. 677-680 (1980).
Hunter et al., “The Adjuvant Activity of Nonionic Block Polymer Surfactant. I. The Role of Hydrophile-Lipophile Balance,”J. Immunol., vol. 127, No. 3, pp. 1244-1250 (1981).
Hunter et al. “The Adjuvant Activity of Nonionic Block Polymer Surfactant. III. Characterization of Selected Biologically Active Surfaces,”Scand. J. Immunol., vol. 23, pp. 287-300 (1986).
Hunter, et al., “Adjuvant activity of non-ionic block copolymers. IV. Effect of molecular weight and formulation on titre and isotype of antibody,”Vaccine, vol. 9, pp. 250-256 (Apr. 1991).
Lopez, et al., “Polymerization of Some Oxiranes Using the Diphenylzinc-Butanone System in Benzene at60° C.,”Polymer International, vol. 24, No. 2, pp. 105-112 (1991).
Lowe, A.J., et al., “Some Effects of Molecular Structure on the Production of Flexible Urethane Foam,”J. Cellular Plastics, vol. 1(1), pp. 121-131 (1965).
Malkemus, “Production of Alkylene Oxide Derivatives,”The Journal of the American Oil Chemists' Society, vol. 33, pp. 571-574 (1956).
Newman, et al., “Increasing the Immunogenicity of a Trivalent Influenza Virus Vaccine with Adjuvant-active Nonionic Block Copolymers for Potential Use in the Elderly,”Mechanisms of Aging and Development, vol. 93, pp. 189-203 (1997).
Reisch, et al., “HMW Polyether Polyols Yield Improved PU Cast Elastomers and Sealants,” Elastomerics, pp. 18-23 (1991).
Reisch, et al., “Polyurethane Sealants and Cast Elastomers with Superior Physical Properties,”33rdAnnual Polyurethane Technical/Marketing Conference, pp. 368-373 (Sep. 30-Oct. 3, 1990).
Schick, M.J., “Nonionic Surfactants,” Solvent Properties of Surfactant Solutions, vol. 2, pp. 10-13, 20-23, 26-29.
Schuchardt, et al., “Preparation of High Molecular Weight Polyols Using Double Metal Cyanide Catalysts,”32ndAnnual Polyurethane Technical/Marketing Conference, pp. 360-364 (Oct. 1-4, 1989).
Shachat, et al., “Mechanism of Ethylene Oxide Condensation,”Nonionic Surfactants, vol. 2, pp. 10-29 (1967).
Smith, et al., “Thermoplastic Polyurethane Elastomers Made from High Molecular Weight POLY-L™ Polyols,”Polyurethanes World Congress, 1991, pp. 313-318 (Sep. 24-26, 1991).
Todd, et al., “Development of an Adjuvant-Active Nonionic Block Copolymer for use in Oil-Free Subunit Vaccine Formulations,”Vaccine, vol. 15, No. 5, pp. 564-570 (1997).
Triozzi, et al., “Effects of a β-Human Chorionic Gonadotropin Subunit Immunogen Administered in Aqueous Solution with a Novel Nonionic Block Copolymer Adjuvant in Patients with Advanced Cancer,”Clinical Cancer Research, vol. 3, pp. 2355-2362 (1997).
Wu, et al., “New Catalyst Systems of Rare Earth Actylacetonate/AIEt3-1/2 H2O for Polymerization of Propylene Oxide,”J. Polymer Sci., vol. 28, pp. 1995-1997 (1990).
The Pluronic Grid, 6thEd., Wyandotte Chemicals Corp., Wyandotte, Michigan (1968).
“The Synthesis and Properties of Block Copolymer Polyol Surfactants,”Block and Graft Copolymerization, R.J. Ceresa, eds., John Wiley & Sons (London), pp. 13-21 (1976).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Adjuvants and copolymer compositions does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adjuvants and copolymer compositions, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adjuvants and copolymer compositions will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-3384672

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.