Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1995-04-14
1996-11-19
Mullis, Jeffrey C.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424468, 424469, 424470, 424497, 424493, A61K 4730, A61K 4726
Patent
active
055760201
ABSTRACT:
A polyester represented by the following general formula (I) and a copolymer which comprises two structural units represented by the following general formulae (I') and (II). ##STR1## and a coating material for use in large intestine-selective drug release pharmaceutical preparations, which contains the above polyester and/or copolymer. The polyester and copolymer of the present invention contain a saccharide residue which is hydrolyzed and/or assimilated specifically in the large intestine, drugs contained in solid oral pharmaceutical administration pharmaceutical preparations coated with the coating material of the present invention are not decomposed or absorbed by digestive organs other than the large intestine, but instead are released selectively and therefore in a high concentration in the large intestine.
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Iritani Koji
Kawasaki Tetsuya
Masuda Shigeki
Tani Nobutaka
Yano Yoshiaki
Kanegafuchi Kagaku Kogyo & Kabushiki Kaisha
Mullis Jeffrey C.
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