Adjuvant-containing vaccines

Details Adjuvant-containing vaccines Adjuvant-containing vaccines

2007-01-16

2007-01-16

Nguyen, Dave Trong (Department: 1632)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Carbohydrate doai

C424S450000, C424S486000, C424S468000, C435S320100

Reexamination Certificate

active

09677672

ABSTRACT:
This invention provides a DNA vaccine which comprises a naked DNA incorporating and expressing in vivo a nucleotide sequence encoding an antigenic polypeptide, preferably a gene of a pathogenic agent, and at least one adjuvant compound chosen from the polymers of acrylic or methacrylic acid and copolymers of maleic anhydride and alkenyl derivative. The adjuvant compound is preferably a carbomer or an EMA®. This invention also provides a method of enhancing a DNA vaccine and/or the immunogenicity of a DNA vaccine.

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