Adjustment of the sample support in time-of-flight mass spectrom

Details Adjustment of the sample support in time-of-flight mass spectrom Adjustment of the sample support in time-of-flight mass spectrom

1997-08-14

1999-06-08

Nguyen, Kiet T.

Radiant energy

Ionic separation or analysis

Ion beam pulsing means with detector synchronizing means

2502521, H01J 4904

Patent

active

059106565

ABSTRACT:
A time-of-flight mass spectrometers, in which the ions are generated by ionization of analyte substances on a sample support, by matrix-assisted laser desorption (MALDI). The time-of-flight mass spectrometer consists of using space-adjusting actuators to set the spacing of the sample support from the nearest acceleration electrode so that the flight time of ions of a reference substance prescribed by the calibration can be precisely adjusted. Due to this adjustment of the spacing, a once only calibration of the relationship between the flight time and mass (i.e. the mass scale) may be constantly retained.

REFERENCES:
patent: 4243887 (1981-01-01), Hillenkamp et al.
patent: 4740692 (1988-04-01), Yamamoto et al.
patent: 5498545 (1996-03-01), Vestal
Robert S. Brown et al, Mass Resolution Improvement by Incorporation of Pulsed Ion Extraction in a Matrix-Assisted Laser Desorption/Ionization Linear Time-of-Flight Mass Spectrometer, Analytical Chemistry, vol. 67, No. 13, pp. 1998-2003, Jul. 1, 1995.
Johann M. Grunderwurmer et al., High-resolution mass spectrometry in a linear time-of-flight mass spectrometer, International Journal of Mass Spectrometry and Ion Processes, vol. 131, pp. 139-148, 1994.

Affiliated with

Also associated with

Rating

Adjustment of the sample support in time-of-flight mass spectrom does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adjustment of the sample support in time-of-flight mass spectrom, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adjustment of the sample support in time-of-flight mass spectrom will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1684476