Adjacently substituted ketal derivatives of cycloalkane-amide an

Details Adjacently substituted ketal derivatives of cycloalkane-amide an Adjacently substituted ketal derivatives of cycloalkane-amide an

1982-11-04

1984-07-17

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

560250, 560251, 560255, 424226, 424267, 424244, 424301, 424309, 424311, 424324, 548578, 546234, 260239A, 260349, 564162, 564163, 564164, 564165, 564166, 564182, 564183, A61K 3140, C07D48700

Patent

active

044606001

ABSTRACT:
Cis- and trans-N-[2-amino(adjacenty substituted bis(alkyloxy), bis(alkylthio), alkylthio or mercapto group substituted)-cycloaliphatic]benzeneacetamide and -benzamide compounds, e.g., (.+-.)-(1.alpha.,2.beta.)-4-bromo-N-[3,3-dimethoxy-2-(1-pyrrolidinyl)cyclo hexyl]-N-methylbenzamide, and salts thereof, are provided. These compounds have analgesic properties. Processes for their preparation are disclosed. Pharmaceutical compositions and methods of use are also provided.

REFERENCES:
patent: 3510492 (1970-05-01), Szmuszkovicz
patent: 4065573 (1977-12-01), Lednicer
patent: 4098904 (1978-07-01), Szmuszkovicz
patent: 4145435 (1979-03-01), Szmuszkovicz
patent: 4212878 (1980-07-01), Lednicer
patent: 4359476 (1982-11-01), Kaplan et al.

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