Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Patent
1996-12-12
1998-04-14
Elliott, George C.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
4352523, 4353201, 435325, 530350, 536 235, C12N 510, C12N 1512, C12N 1586, C07K 14435
Patent
active
057390096
ABSTRACT:
The present invention provides a human adipocyte-specific differentiation-related protein (HADRP) and polynucleotides which identify and encode HADRP. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding HADRP and a method for producing HADRP. The invention also provides for agonists, antibodies, or antagonists specifically binding HADRP, and their use, in the prevention and treatment of diseases associated with expression of HADRP. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding HADRP for the treatment of diseases associated with the expression of HADRP. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding HADRP.
REFERENCES:
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Hawkins Phillip R.
Hillman Jennifer L.
Billings Lucy J.
Elliott George C.
Incyte Pharmaceuticals Inc.
Railey II Johnny F.
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