Adhesive patch for percutaneous delivery of isosorbide dinitrate

Details Adhesive patch for percutaneous delivery of isosorbide dinitrate Adhesive patch for percutaneous delivery of isosorbide dinitrate

1994-05-16

1995-05-30

Phelan, D. Gabrielle

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Web, sheet or filament bases; compositions of bandages; or...

424448, 514946, 514947, 514969, A61F 1300

Patent

active

054199123

ABSTRACT:
An adhesive patch for percutaneous delivery of isosorbide dinitrate includes a piece of separating paper; a percutaneous salve preparation which is solvent free and which is comprised of: (a) isosorbide dinitrate; (b) a percutaneous absorption accelerator which is at least one substance selected from the group consisting of a chained monocarboxylate and a higher alcohol; and (c) a tackifier composition as an additive, wherein the chained monocarboxylate is selected from the group consisting of isopropyl palmitate, isopropyl myristate, cetyl lactate, diethyl sebacate, xylol laurate, cetyl isooctanoate and lauryl lactate, wherein the higher alcohol is selected from the group consisting of cetanol, stearyl alcohol, lauryl alcohol, cetostearyl alcohol and myristyl alcohol, and wherein the percutaneous absorption accelerator is present in an amount ranging between 3 and 12 wt % if a chained monocarboxylate is used and between 1 and 3 wt % if a higher alcohol is used; and a surface coating material which is polymeric.

REFERENCES:
patent: 4485087 (1984-11-01), Otsuka
patent: 5176916 (1993-01-01), Yamanaka
patent: 5204109 (1993-04-01), Akemi
European Search Report, EP 93 87 0051, May 6th, 1993.

Affiliated with

Also associated with

Rating

Adhesive patch for percutaneous delivery of isosorbide dinitrate does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adhesive patch for percutaneous delivery of isosorbide dinitrate, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adhesive patch for percutaneous delivery of isosorbide dinitrate will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-360000