Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Reexamination Certificate
2007-07-03
2007-07-03
Crane, L. E. (Department: 1623)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
C435S325000
Reexamination Certificate
active
11103354
ABSTRACT:
The present invention relates to a method of inhibiting cellular and protein attachment to substrates by applying a composition containing an effective amount of adherent N,O-carboxymethylchitosan to a substrate with such that cellular and protein attachment are prevented or greatly reduced.
REFERENCES:
patent: 4424346 (1984-01-01), Hall et al.
patent: 4603695 (1986-08-01), Ikada et al.
patent: 4615697 (1986-10-01), Robinson
patent: 4619995 (1986-10-01), Hayes
patent: 4659700 (1987-04-01), Jackson
patent: 4868113 (1989-09-01), Jaye et al.
patent: 4886787 (1989-12-01), De Belder et al.
patent: RE33375 (1990-10-01), Luck et al.
patent: 4978332 (1990-12-01), Luck et al.
patent: 5080893 (1992-01-01), Goldberg et al.
patent: 5093319 (1992-03-01), Hingham et al.
patent: 5234915 (1993-08-01), Mathur et al.
patent: 5412084 (1995-05-01), Elson
patent: 5510102 (1996-04-01), Cochrum
patent: 5578661 (1996-11-01), Fox et al.
patent: 5679658 (1997-10-01), Elson
patent: 5840777 (1998-11-01), Eagles et al.
patent: 5851461 (1998-12-01), Bakis et al.
patent: 5888988 (1999-03-01), Elson
patent: 5948401 (1999-09-01), Donabedian et al.
patent: 6030635 (2000-02-01), Gertzman et al.
patent: 6197325 (2001-03-01), MacPhee et al.
patent: 6224794 (2001-05-01), Amsden et al.
patent: 6645947 (2003-11-01), Elson et al.
patent: 6894035 (2005-05-01), Elson et al.
patent: 19604180 (1997-08-01), None
patent: 19724869 (1998-12-01), None
patent: 0312208 (1989-04-01), None
patent: 0368253 (1990-05-01), None
patent: 0637450 (1995-02-01), None
patent: 0650999 (1995-05-01), None
patent: 0665022 (1995-08-01), None
patent: WO 86/00912 (1986-02-01), None
patent: WO86/00912 (1986-02-01), None
patent: WO 87/07618 (1987-12-01), None
patent: WO87/07618 (1987-12-01), None
patent: WO 93/13137 (1993-07-01), None
patent: WO93/13137 (1993-07-01), None
patent: WO96/02258 (1996-02-01), None
patent: WO 96/02258 (1996-02-01), None
patent: WO96/13282 (1996-05-01), None
patent: WO 96/13284 (1996-05-01), None
patent: WO96/13284 (1996-05-01), None
patent: WO98/50050 (1998-11-01), None
patent: WO00/71136 (2000-11-01), None
patent: WO01/98206 (2001-12-01), None
Tarsi et al., “Inhibition ofStreptococcus mutansAdsorption to Hydroxyapatite by Low-molecular-weight Chitosans,” Journal of Dental Research, 76(2), 665-672 (Feb. 1997).
D. Venes et al. (eds.), TaberÖs Cyclopedic Medical Dictionary, 19th Edition, F. A. Davis Co., Philadelphia, PA, 2001, only pp. 46, 47, 750 and 1077 supplied.
Sanzgiri et al., “Targeting Polysaccharide-Methotrexate Conjugates to the Rat Brain,” Polymers for Advanced Technologies, 3(6), 317-321 (1992 ); Chemical Abstracts, 121(2), p. 582, Abstr. No. 17814h (Jul. 11, 1994).
D. Venes et al. (eds.),Taber's Cyclopedic Medical Dictionary, 19th Edition, F. A. Davis Co., Philadelphia, PA, 2001, only pp. 46, 47, 750 and 1077 supplied.
Sanzgiri et al., “Targeting Polysaccharide-Methotrexate Conjugates to the Rat Brain,”Polymers for Advanced Technologies, 3(6), 317-321 (1992†);Chemical Abstracts, 121(2), p. 582, Abstr. No. 17814h (Jul. 11, 1994).
Brecht, M. et al., “Increased hyaluronate synthesis is required for fibroblast detachment and mitosis,”Biochem, J.239:445-450 (1986).
Docherty, R. et al., “Glycosaminoglycans facilitate the movement of fibroblasts through three-dimensional collagen matrices,”J. Cell Sci.92:213-270 (1989).
Hoekstra, D., yaluronan-modified surfaces for medical devices,Medical devices&diagnostic Industry, 48-58 (1989); (Feb. 1999).
Lynn, L.H. et al., “Effects of hyaluronan on collagen fibrillar matrix contraction by fibroblasts,”J. of Biomedical Materials Research, 28:123-132 (1994).
Aldemann-Grill et al. (1990) “Chemotactic Migration of Normal Dermal Fibroblasts Towards Epidermal Growth Factor and Its Modulation by Platelet-Derived Growth Factor and Transforming Growth Factor-Beta”Eur. J. Cell Biol.51:322-326;(Iss. No. 2, Apr. 1990).
Borah et al. (1995) “Wound Epithelialization is Accelerated by N,O-Carboxymethyl Chitosan”Amereican Burn Assoc. 27th Annual Mtg.,Albuquerque, NM; (Apr. 1995).
Buchholz et al. (1984) “Antibiotic-loaded Acrylic Cement: Current Concepts”Clin. Orthop.&Rel. Res.190:96-108; (Nov. 1984).
Buchholz et al. (1981) “Management of Deep Infection of Total Hip Replacement”J. Bone&Joint Surgery63B(3):342-353.
Canalis et al. (1988) “Growth Factors and the Regulation of Bone Remodeling”J. Clin. Invest.81:277-281; (Feb. 1988; Issue No. 2).
Chandrasekaran et al. (1982) “Dissolution-Controlled Transport from Dispersed Matrixes”J. Pharmaceut. Sci.71(12):1399-1402; (Dec. 1982).
Chandy et al. (1991) “Biodegradable Chitosan Matrix for the Controlled Release of Steroids”Biomat., Art. Cells&Immob. Biotech.19(4):745-760.
Christian et al. (1989) “Reconstruction of Large Diaphyseal Defects, without Free Fibular Transfer, in Grade-IIIB Tibial Fractures”J. Bone&Joint Surg.71-A(7):994-1004; (Aug. 1989).
Dash et al. (1992) “An Implantable Dosage Form for the Treatment of Bone Infections”Pharmaceutical Research9(8):993-1002; (Aug. 1992).
Davies et al. (1988) “N, O-Carboxymethl Chitosan, A New Water Soluble Chitin Derivative”Proceed. Int'l Chitin-Chitosan Conference; Aug. 22-24, 1988; Trondheim, Norway.
Golub et al. (1994) “Treating Peridontal Diseases by Blocking Tissue-Destructive Enzymes”JADA125:163-171; (Feb. 1994).
Goodson et al. (1983) “Monolithic Tetracycline-containing Fibers for Controlled Delivery to Periodontal Pockets”J. Periodontol.54(10):575-579; (Oct. 1983).
Greco et al. (1991) “Fibrin-antibiotic mixtures: An in vitro study assessing the possibility of using a biological carrier for local drug delivery”J. Biomed. Mat. Res.25(1):39-51;(Jan. 1991).
Greenhalgh et al. (1990) “PDGF and FGF Stimulate Wound Healing in Genetically Diabetic Mouse”Amer. J. Pathol.136(6):1235-1246; (Jun. 1990).
Hattori (1990) “Bone Morphogenetic Protein-BMP: Experimental Investigations of Osteogenesis and Chondrogenesis by Implant of BMP-Fibrin Glue Mixture”J. Jpn. Orthop. Assoc.64:824-834;(Sep. 1990).
Hauschka et al. (1986) “Growth Factors in Bone Matrix”J. Biol. Chem.261(27):12665-12674; (Sep. 25, 1986).
Hayek et al. (1987) “An In Vivo Model For Study of the Angiogenic Effects of Basic Fibroblast Growth Factor”Biochem.&Biophys. Res. Comm.147(2):876-880; (Sep. 15, 1987).
Higuchi (1963) “Mechanism of Sustained-Action Medication-Theoretical Analysis of Rate of Release of Solid Drugs Dispersed in Solid Matrices”J. Pharmaceut. Sci.52(12):1145-1149; (Dec. 1963).
Kawamura et al. (1988) “Human Fibrin is a Physiologic Delivery System for Bone Morphogenetic Protein”Clin. Orthop.&Rel. Res.235:302-310: (Oct. 1988).
Klokkevold et al. (1992) “Effect of Chitosan on Lingual Hemostasis in Rabbits with Platelet Dysfunction Induced by Epoprostenol”J. Oral Maxillofac. Surg.50:41-45;(Jan. 1992).
Knighton et al. (1986) “Classification and Treatment of Chronic Nonhealing Wounds”Ann. Surg.204(3):322-330; (Sep. 1986).
Kram et al. (1991) “Antibacterial Effects of Fibrin Glue-Antibiotic Mixtures”J. Surg. Res: 50:175-178;(Feb. 1991).
Kristl et al. (1993) “Hydrocolloids and Gels of Chitosan as Drug Carriers”Int'l J. Pharmaceut.99:13-19.
Ksander et al. (1990) “The Effect of Platelet Releasate on Wound Healing in Animal Models”Amer. Acad. Dermatol.22(5):781-791; (Part 1, May 1990).
Luyten et al. (1989) “Purification and Partial Amino Acid Sequence of Osteogenin, a Protein Initiating Bone Differentiation”J. Biol. Chem.264(23):13377-13380; (Aug. 15, 1989).
Lynch et al. (1989) “Growth Factors in Wound Healing”J. Clin. Invest.84:640-646; (Aug. 1989).
Mackey et al. (1982) “Antibiotic Loaded Plaster of Paris Pellets”Clin. Orthop.&Rel. Res.167:263-268;
Elson Clive
Lee Timothy D. G.
Chitogenics, Inc.
Crane L. E.
Edwards Angell Palmer & & Dodge LLP
Loren, Esq. Ralph A.
LandOfFree
Adhesive N,O-carboxymethylchitosan coatings which inhibit... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Adhesive N,O-carboxymethylchitosan coatings which inhibit..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adhesive N,O-carboxymethylchitosan coatings which inhibit... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3742379