Adhesion receptor antagonists

Details Adhesion receptor antagonists Adhesion receptor antagonists

1995-11-07

1998-07-07

Bernhardt, Emily

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514212, 514316, 514326, 540597, 540598, 544357, 544364, 544369, 544367, 544370, 546187, 546209, 546210, A61K 31495, C07D41314

Patent

active

057769370

ABSTRACT:
Compounds of the formula I ##STR1## wherein R.sup.1 and Y have the meanings indicated, and also their physiologically acceptable salts, inhibit the binding of fibrinogen to the corresponding receptor and can be employed for the treatment of thromboses, osteoporoses, oncoses, apoplexy, cardiac infarct, inflammations, arteriosclerosis and osteolytic disorders.

REFERENCES:
patent: 4970217 (1990-11-01), Prucher et al.
patent: 5232931 (1993-08-01), Prucher et al.
patent: 5561148 (1996-10-01), Gante et al.
P. Valentin-Weigand et al., "Mediation of Adherence of Streptococci to Human Endothelial Cells by Complement S Protein (Vitronectin), " Infection and Immunity, 56(11):2851-2855 (Nov. 1988).
Born, "Aggregation of Blood Platelets by Adenosine Diphosphate and Its Reversal," Nature, 4832:927-929 (Jun. 9, 1962).
Gante et al, Chemical Abstracts, vol. 124, No. 105615 (1996).
Gante et al, Lett. Pept. Sci. 2, pp. 135-140 (1995).
Muller et al in Receptor Data for Biological Experiments (by Doods & Meel), pp. 112-117 (1991).

Affiliated with

Also associated with

Rating

Adhesion receptor antagonists does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Adhesion receptor antagonists, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Adhesion receptor antagonists will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1206163