Adhesion deficient isolate of Flavobacterium columnare...

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

Reexamination Certificate

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C435S243000, C435S245000

Reexamination Certificate

active

06984388

ABSTRACT:
A safe and effective live vaccine againstFlavobacterium columnareof fish was created through the induction of an adhesion deficient isolate ofFlavobacterium columnareusing a β-lactam antibiotic (ampicillin). Single immersion exposure of fish stimulated acquired immunity against virulentF. columnareinfection.

REFERENCES:
patent: 5284653 (1994-02-01), Wolf-Watz et al.
Colman, Res. Immunology, Jan. 1994, vol. 145, pp. 33-36.

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