Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Implant or insert
Patent
1997-06-23
2000-08-29
Williamson, Michael A.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Implant or insert
424 9464, 424 7824, 424 7827, 514834, 514781, 623 1, 623 3, 604187, 604313, 604319, 427 23, 427569, 427421, 427429, 4274301, A61F 202
Patent
active
061104833
ABSTRACT:
The adherent coating of the invention comprises a stabilizing polymer together with an active agent (a hydrophilic polymer and/or a bioactive agent) in a layer bonded to the surface of a medical device. This invention encompasses the coating liquids used for coating medical devices, methods of coating the devices, and the coated devices. The stabilizing polymer is selected to entrap the active agent in a coating that has a high degree of flexibility and has improved bonding to a wide variety of substrates. Preferred stabilizing polymers are cross-linkable acrylic and methacrylic polymers, ethylene acrylic acid copolymers, styrene acrylic copolymers, vinyl acetate polymers and copolymers, vinyl acetal polymers and copolymers, epoxy, melamine, other amino resins, phenolic polymers, copolymers thereof, and combinations.
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Whitbourne Richard J.
Zhang Xianping
Gollin Michael A.
STS Biopolymers, Inc.
Williamson Michael A.
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