Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor
Reexamination Certificate
2008-03-11
2008-03-11
Prouty, Rebecca E. (Department: 1652)
Chemistry: molecular biology and microbiology
Micro-organism, per se ; compositions thereof; proces of...
Bacteria or actinomycetales; media therefor
C435S006120, C435S007200, C435S069100, C435S471000, C435S189000, C435S155000, C536S023200
Reexamination Certificate
active
07341859
ABSTRACT:
The present invention relates to an alcohol dehydrogenase fromRhodococcus erythropolis. By means of such cofactor-dependent ADHs, chiral alcohols, which can be of use for use in organic syntheses, can advantageously be obtained with a cofactor-regenerating enzyme in a coupled enzymatic system. A nucleotide sequence, vehicles containing this, a polypeptide sequence and processes for mutation and use of the sequences are claimed.
REFERENCES:
patent: 2003/0100065 (2003-05-01), Hummel et al.
patent: 2003/0224279 (2003-12-01), Kotsugai et al.
patent: 2005/0064570 (2005-03-01), Hummel et al.
patent: 2006/0216801 (2006-09-01), Groger et al.
patent: 2006/0246561 (2006-11-01), Hummel et al.
patent: 2007/0149781 (2007-06-01), Riermeier et al.
patent: 42 09 022 (1993-10-01), None
patent: 1 201 647 (2002-05-01), None
patent: 1 213 354 (2002-06-01), None
Hummel et al. Towards a Large-Scale Asymmetric Reduction Process with Isolated Enzymes: Expression of an (S)-Alcohol Dehydrogenase inE. coliand Studies on the Synthetic Potential of this Biocatalyst, Adv. Synth. Catal. 345, Jan. 21, 2003.
Wang, J.-C. et al. “Cloning, sequence analysis and expression inEscherichia coliof the gene encoding phenylacetaldehyde reductase from styrene-assimilating Corynebacterium sp. Strain ST-10”, Appl. Microbiol. Biotechnol., vol. 52, No. 3, pp. 386-392, XP002221908 1999.
Itoh, Nobuya et al. “Purification and Characterization of Phenylacetaldehyde Reductase from a Styrene- Assimilating Corynebacterium Strain, ST-10”, Applied and Environmental Microbiology, vol. 63, No. 10, pp. 3783-3788, XP002221910 1997.
Itoh, Nobuya et al. “Production of Chiral Alcohols by Enantioselective Reduction with NADH-dependent phenylacetaldehyde reductase from Corynebacterium strain, ST-10”, Journal of Molecular Catalysis B: Enzymatic, vol. 6, No. 1-2, pp. 41-50, XP002221909 1999.
Hummel, Werner. “New Alcohol Dehydrogenases for the Synthesis of Chiral Compounds”, Advances in Biochemical Engineering/Biotechnology, vol. 58, pp. 145-184, XP000677754 1997.
Schenkels, Peter et al. “Nicotinoprotein (NADH-containing) alcohol dehydrogenase fromRhodococcus erythropolisDSM 1069: an efficient catalyst for coenzyme-independent oxidation of a broad spectrum of alcohols and the interconversion of alcohols and aldehydes”, Microbiology, vol. 146, No. 4, pp. 775-785, XP002253322 2000.
Reid, Matthew F. et al. “Molecular Characterization of Microbial Alcohol Dehydrogenases”, Critical Reviews in Microbiology, vol. 20, No. 1, pp. 13-56, XP002110760 1994.
Hummel, W. et al., “Chiral Alcohols by Enantioselective Enzymatic Oxidation”, Annals New York Academy of Sciences, vol. 799, pp. 713-716, XP000677513 1996.
U.S. Appl. No. 11/766,164, filed Jun. 21, 2007, Groeger et al.
U.S. Appl. No. 11/766,189, filed Jun. 21, 2007, Groeger et al.
U.S. Appl. No. 11/736,351, filed Apr. 17, 2007, Yamaguchi et al.
U.S. Appl. No. 11/629,407, filed Dec. 13, 2006, Groeger et al.
U.S. Appl. No. 10/521,445, filed Jan. 14, 2005, Groeger et al.
U.S. Appl. No. 10/521,456, filed Jan. 18, 2005, Groeger et al.
U.S. Appl. No. 10/508,702, filed Sep. 29, 2004, Hummel et al.
U.S. Appl. No. 10/546,733, filed Aug. 24, 2005, Rollmann et al.
U.S. Appl. No. 10/492,939, filed Apr. 19, 2004, May et al.
U.S. Appl. No. 10/508,702, filed Jul. 11, 2005, Hummel et al.
U.S. Appl. No. 10/593,567, filed Sep. 20, 2006, Groeger et al.
Abokitse Kofi
Groeger Harald
Hummel Werner
Chowdhury Iqbal
Degussa - AG
Oblon & Spivak, McClelland, Maier & Neustadt P.C.
Prouty Rebecca E.
LandOfFree
ADH from Rhodococcus erythropolis does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with ADH from Rhodococcus erythropolis, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and ADH from Rhodococcus erythropolis will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2783912