Drug – bio-affecting and body treating compositions – Whole live micro-organism – cell – or virus containing – Virus or bacteriophage
Patent
1995-06-07
2000-09-19
Chambers, Jasemine C.
Drug, bio-affecting and body treating compositions
Whole live micro-organism, cell, or virus containing
Virus or bacteriophage
424 931, 4353201, 435440, 435455, 514 44, A01N 6300, A01N 4304, C12N 1563, C12N 1586
Patent
active
061207640
ABSTRACT:
The invention claims a class of adenovirus vectors for delivering recombinases to a large number of cells of different origins, and methods for regulating the expression of a gene in transfected mammalian cells in culture and in cells of transgenic animals, comprising infecting said cells with an Ad vector encoding a recombinase whose target site is present at or adjacent to the gene, wherein the action of the recombinase regulates the expression of said gene.
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Anton Martina
Bacchetti Silvia
Graham Frank L.
Muller William J.
Rudnicki Michael A.
AdVec, Inc.
Bencen Gerard H.
Chambers Jasemine C.
Clark Deborah J. R.
Van Dyke Timothy H.
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